Calcium channels blockers in the treatment of leiomyomas

Leiomyomas are benign tumors arising from smooth muscle ( myo- refers to muscle). They can develop from anywhere in the body, but are more common in the uterus. Leiomyomas arising from the uterus cause menorrhagia (excessive menstrual bleeding, which will result in anemia, and if nor corrected.

Researchers have developed several medications to correct this condition which might lead to infertility in women. Although some of those medications work properly, they are not really effective in reducing physical pain associated with those benign tumors.

But investigators reported that calcium channels blockers, are very efficient in alleviating pain associated with different types of leiomyomas. medications that belong to that class of chemicals include: Nifedipin, gabapentin, and phenoxybenzamine. Moreover, it has been said that botulinum toxin might have some pain relief properties for leiomyomas; but this hypothesis still needs to be verified.